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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STX1A
All Species:
26.97
Human Site:
S99
Identified Species:
45.64
UniProt:
Q16623
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16623
NP_004594.1
288
33023
S99
K
L
K
S
I
E
Q
S
I
E
Q
E
E
G
L
Chimpanzee
Pan troglodytes
XP_001146754
288
33051
S99
Q
Q
Q
S
I
E
Q
S
I
E
Q
E
E
G
L
Rhesus Macaque
Macaca mulatta
NP_001028037
288
32987
P99
K
L
K
S
I
E
Q
P
I
E
Q
E
A
G
L
Dog
Lupus familis
XP_849756
293
33456
S104
K
L
K
S
I
E
Q
S
I
E
Q
E
E
G
L
Cat
Felis silvestris
Mouse
Mus musculus
O35526
288
33036
S99
K
L
K
S
I
E
Q
S
I
E
Q
E
E
G
L
Rat
Rattus norvegicus
P32851
288
33049
S99
K
L
K
S
I
E
Q
S
I
E
Q
E
E
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233551
316
35842
S127
K
L
K
S
I
E
Q
S
I
E
Q
E
E
G
L
Frog
Xenopus laevis
NP_001086322
286
32704
E97
R
S
R
L
K
A
M
E
Q
S
I
E
Q
D
D
Zebra Danio
Brachydanio rerio
NP_571598
288
33347
S98
K
L
K
A
I
E
Q
S
I
E
Q
E
E
G
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24547
291
33630
N102
K
L
K
G
I
E
Q
N
I
E
Q
E
E
Q
Q
Honey Bee
Apis mellifera
XP_393760
291
33455
N103
K
L
K
V
I
E
Q
N
I
E
Q
E
E
H
T
Nematode Worm
Caenorhab. elegans
O16000
291
33234
N100
G
K
L
K
L
I
E
N
A
I
D
H
D
E
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SRV7
306
34701
N110
L
D
R
E
N
L
E
N
R
T
K
P
G
C
G
Baker's Yeast
Sacchar. cerevisiae
P39926
295
33715
L98
A
T
D
L
Q
Y
Q
L
K
A
D
I
K
D
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93
98.9
93.1
N.A.
98.2
98.6
N.A.
N.A.
85.7
67.3
82.9
N.A.
70
69.4
63.2
N.A.
Protein Similarity:
100
95.4
98.9
94.5
N.A.
98.9
99.3
N.A.
N.A.
89.8
85.7
93.4
N.A.
83.1
81.4
80
N.A.
P-Site Identity:
100
80
86.6
100
N.A.
100
100
N.A.
N.A.
100
6.6
93.3
N.A.
73.3
73.3
0
N.A.
P-Site Similarity:
100
93.3
86.6
100
N.A.
100
100
N.A.
N.A.
100
26.6
100
N.A.
80
80
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.2
24.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
51.3
47.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
8
0
0
8
8
0
0
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
8
8
0
0
0
0
0
0
0
15
0
8
15
8
% D
% Glu:
0
0
0
8
0
72
15
8
0
72
0
79
65
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
8
0
0
0
0
0
0
0
0
8
58
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% H
% Ile:
0
0
0
0
72
8
0
0
72
8
8
8
0
0
0
% I
% Lys:
65
8
65
8
8
0
0
0
8
0
8
0
8
0
0
% K
% Leu:
8
65
8
15
8
8
0
8
0
0
0
0
0
0
58
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
29
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% P
% Gln:
8
8
8
0
8
0
79
0
8
0
72
0
8
8
15
% Q
% Arg:
8
0
15
0
0
0
0
0
8
0
0
0
0
0
0
% R
% Ser:
0
8
0
50
0
0
0
50
0
8
0
0
0
0
0
% S
% Thr:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
8
% T
% Val:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _